Education
2005-2009, Shandong Agricultural University, Bioengineering, Bachelor
2009-2012, Beijing Institute of Genomics, Chinese Academy of Sciences, Genomics, Master
2012-2015, Beijing Institute of Genomics, Chinese Academy of Sciences, Bioinformatics, Ph.D
Research experiences
2015-2018, College of Marine Life Science, Ocean University of China, Molluscan Genomics, Postdoc
2019-Present, College of Marine Life Sciences, Ocean University of China, Associate Professor
Main research directions and interests
Main research interest is molluscan genomics, focusing on three aspects: 1) Genetic analysis of mollusca evolution and adaptation; 2) Construction of multiomics database; 3) Development of advanced genomics technology and methods.
Representative publications (#equal contribution; *corresponding author)
1. Li Y#, Liu Y#, Yu H, Liu F, Han W, Zeng Q, Zhang Y, Zhang L, Hu J, Bao Z & Wang S*. Adaptive bird-like genome miniaturization during the evolution of scallop swimming lifestyle. Genomics, Proteomics & Bioinformatics. 2022, 20: 1066-1077.
2. Han W#, Liu L#, Wang J#, Wei H#, Li Y#, Zhang L#, Guo Z, Li Y, Liu T, Zeng Q, Xing Q, Shu Y, Wang T, Yang Y, Zhang M, Li R, Yu J, Pu Z, Lv J, Lian S, Hu J, Hu X, Bao Z, Bao L*, Zhang L* & Wang S*. Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation. Nature Ecology & Evolution. 2022, 6: 1891–1906.
3.Liu F, Li Y*, Yu H, Zhang L, Hu J, Bao Z &Wang S*. MolluscDB: an integrated functional and evolutionary genomics database for the hyper-diverse animal phylum Mollusca. Nucleic Acids Research. 2021, 49: D988-D997.
4. Wang J#, Yu H#, Yao L#, Li Y*, Liu F, Han W, Cui C, Hu J, Bao Z &Wang S*. Genomic and transcriptomic landscapes and evolutionary dynamics of molluscan glycoside hydrolase families with implications for algae-feeding biology. Computational and Structural Biotechnology Journal. 2020, 18: 2744-2756.
5. Li Y#, Sun X#, Hu X#, Jiao W#, Xun X#, Zhang J#, Guo X#, Zhang L, Liu W, Wang J, Li J, Sun Y, Miao Y, Cheng T, Xu GL, Fu X, Wang Y, Yu X, Huang X, Lu W, Lv J, Mu C, Wang D, Li X, Xia Y, Li YP, Yang Z, Wang F, Zhang L, Xing Q, Dou H, Ning X, Dou J, Li Y, Kong D, Liu Y, Jiang Z, Li R, Wang S* & Bao Z*. Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins. Nature Communications. 2017, 8: 1721.
6. Li Y#, Wang R#, Xun X#, Wang J#, Bao L#, Thimmappa R#, Ding J#, Jiang J#, Zhang L, Li T, Lv J, Mu C, Hu X, Zhang L, Liu J, Li Y, Yao L, Jiao W, Wang Y, Lian S, Zhao Z, Zhan Y, Huang X, Liao H, Wang J, Sun H, Mi X, Xia Y, Xing Q, Lu W, Osbourn A, Zhou Z*, Chang Y*, Bao Z* & Wang S*. Sea cucumber genome provides insights into saponin biosynthesis and aestivation regulation. Cell Discovery. 2018, 4: 29.
7. Li Y#, Wang X#, Chen T#, Yao F, Li C, Tang Q, Sun M, Sun G, Hu S, Yu J & Song S*. RNA-Seq Based De Novo Transcriptome Assembly and Gene Discovery of Cistanche deserticola Fleshy Stem. Plos One. 2015, 10: e0125722.
8. Li Y#, Song S#,*, Wang X, Li C, Hu S & Yu J. Transcriptome-wide N(6)-methyladenosine profiling of rice callus and leaf reveals the presence of tissue-specific competitors involved in selective mRNA modification. RNA Biology. 2014, 11: 1180-1188.
9. Li Y, Song S*, Li C & Yu J. MeRIP-PF: an easy-to-use pipeline for high-resolution peak-finding in MeRIP-Seq data. Genomics Proteomics Bioinformatics. 2013, 11: 72-75.
10. Wang S#, Zhang J#, Jiao W#, Li J#, Xun X#, Sun Y#, Guo X#, Huan P #, Dong B, Zhang L, Hu X, Sun X, Wang J, Zhao C, Wang Y, Wang D, Huang X, Wang R, Lv J, Li Y, Zhang Z, Liu B, Lu W, Hui Y, Liang J, Zhou Z, Hou R, Li X, Liu Y, Li H, Ning X, Lin Y, Zhao L, Xing Q, Dou J, Li YP, Mao J, Guo H, Dou H, Li T, Mu C, Jiang W, Fu Q, Fu X, Miao Y, Liu J, Yu Q, Li R, Liao H, Li X, Kong Y, Jiang Z, Chourrout D*, Li R* & Bao Z*. Scallop genome provides insights into evolution of bilaterian karyotype and development. Nature Ecology & Evolution. 2017, 1: 120.
